Foetal and neonatal outcomes in women reporting ingestion of low or very low alcohol intake during pregnancy

J Matern Fetal Neonatal Med. 2012 Nov;25(11):2186-9. doi: 10.3109/14767058.2012.684107. Epub 2012 May 15.

Abstract

Objective: This study aimed to assess the pregnancy outcomes of women who reported social intake of low or very low alcohol levels during pregnancy.

Methods: Obstetric and foetal outcomes were assessed in a prospective cohort of 1667 pregnant women who reported low or very low alcohol consumption during pregnancy (cases) and 1840 alcohol-abstainer women (controls).

Results: Among cases, alcohol consumption occurred during the first 4.4 (median) weeks of pregnancy, with a median ingestion of 1.0 (0.01-6.0) drinks/week, equivalent to 7.6 (0.09-47.5) g/week. Cigarette smoking was reported approximately four times more often in the exposed group than in the controls (p < 0.001). Pregnancy outcomes were similar between groups. There were 37 (2.4%) babies born with malformations in the exposed group and 41 (2.4%) in the control group (p = 0.9).

Conclusions: Low-to-very low levels of alcohol ingestion during pregnancy do not appear to be associated with adverse maternal or foetal outcomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alcohol Drinking / adverse effects
  • Alcohol Drinking / epidemiology*
  • Case-Control Studies
  • Cohort Studies
  • Drug-Related Side Effects and Adverse Reactions
  • Eating / physiology
  • Ethanol / administration & dosage
  • Ethanol / pharmacology*
  • Female
  • Fetus / drug effects
  • Fetus / physiology
  • Gestational Age
  • Humans
  • Infant, Newborn / physiology
  • Maternal Exposure / statistics & numerical data
  • Pregnancy
  • Pregnancy Outcome / epidemiology*
  • Prenatal Exposure Delayed Effects / epidemiology
  • Prenatal Exposure Delayed Effects / etiology

Substances

  • Ethanol