Use of proton pump inhibitors during pregnancy and breastfeeding > 연구성과

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연구성과

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Achievement

국외
Canadian Family Physician
Use of proton pump inhibitors during pregnancy and breastfeeding
2006
SCI
Alejandro A. Nava-Ocampo, MD, Elvia Y. Velázquez-A

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 [Use of proton pump inhibitors during pregnancy and breastfeeding]

 

Abstract 

Question: A 36-year-old pregnant patient has symptoms of peptic disease. Treatment with diet and lifestyle modifications and also antacids has given her little relief. If she were not pregnant, I would prescribe a proton pump inhibitor (PPI) for her. She is now 4 weeks pregnant, and I need to determine whether PPIs are safe during pregnancy.

Answer: Data currently available suggest that omeprazole is not teratogenic in humans. While information on other PPIs is limited, a systematic review of the evidence suggests that they are also not teratogenic.

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